PDMS EQUIPMENT MODEL TUTORIAL VIDEO from Piping-Info Polydimethylsiloxane called PDMS or dimethicone is a polymer widely used for the dedicated tutorial pages: Basics About Microfluidic Tubings & Sleeves and. Creation and maintenance of AVEVA PDMS project catalogues and specifications for piping, cables, and equipment. Creation or modification of: Catalogue.


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Thus, silicone is a versatile polymer, although its use is often limited by its relatively poor mechanical pdms tutorial.


However, this limitation can be reduced by reinforcing with a silica filler, or by chemical modification of the backbone. The stability, lack of toxicity, and excellent biocompatibility of PDMS makes these pdms tutorial well suited for use in personal care, pharmaceutical, and medical device applications.

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Below is a list of some common properties and uses of silicones. Polar solvents, such as pdms tutorial, struggle to wet the PDMS water beads and does not spread and this leads to the adsorption of hydrophobic contaminants from water on PDMS surface.

This helps making the PDMS hydrophilic for thirty minutes or so. This process also makes the surface resistant to the pdms tutorial of hydrophobic and negatively-charged molecules.

Whether the PDMS surface is plasma oxidized or not, it does not allow water, glycerol, methanol or ethanol infiltration and pdms tutorial deformation.

Thus, it is possible to use PDMS with pdms tutorial fluids without fear of micro-structure deformation. However, the PDMS deforms and swells in the presence of diisopropylamine, chloroform and ether, and also, to a lesser extent, in the presence of pdms tutorial, propanol and pyridine — thus PDMS is not ideal for many organic chemistry applications.

We describe here the fabrication of a microfluidic chip by soft-lithography methods [1].


We obtain a replica of the micro-channels on the PDMS block. The chip is now ready to be connected to microfluidic reservoirs and pumps using microfluidic tubing.

Tygon tubing and Teflon tubing are the most commonly used pdms tutorial on microfluidic setups.


If you are unsure about choosing the appropriate tubing for your setup, see our dedicated tutorial pages: Why pdms tutorial PDMS for microfluidic device fabrication? Human alveolar epithelial and pulmonary microvascular endothelial cells cultivated in a PDMS chip to mimick lung functions It is transparent at optical frequencies nM — nMwhich facilitates the observation of contents pdms tutorial micro-channels visually or through a microscope.


It has a low autofluorescence [2] It is considered as bio-compatible with some restrictions. This allows the production of multilayers PDMS devices to take advantage of the technological pdms tutorial offered by glass substrates, such as the use of metal deposition, oxide deposition or surface functionalization.

PDMS, during cross-linking, can be coated with a controlled thickness on a substrate using a simple spincoat. Pdms tutorial allows the fabrication of multilayer devices and the integration of micro valves.

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It is deformable, which allows the integration pdms tutorial microfluidic valves using the deformation of PDMS micro-channels, the easy connection of leak-proof fluidic connections and its use to detect very low forces like biomechanics interactions from cells.

It is inexpensive compared to previously used materials e. The PDMS is also easy to mold, because, even when mixed pdms tutorial the cross-linking agent, it remains liquid at room temperature for many hours.

The PDMS can mold structures at pdms tutorial resolutions. With some optimization, it is possible to mold structures of a few nanometers [3]. It is gas permeable. PDMS issues for microfluidic applications are: